Alright, fellow Slayers, gather 'round - I've got a story to tell you about the one battle that kept me up at night more than any other in Doom Eternal. We're talking about the Mutated Seraphim, and let me tell you, this guy is no joke. Even in 2025, thinking back on this fight gives me chills. I've seen Ultra-Nightmare runs end in seconds, and honestly? It took me more attempts than I'd like to admit to finally conquer this beast. But hey, that's why I'm here - to make sure you don't make the same mistakes I did.

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Getting Your Gear Straight 🔧

Before we even think about stepping into that arena, let's talk preparation. I learned the hard way that showing up unprepared is basically asking for a quick trip back to the checkpoint.

Must-Have Upgrades:

  • Microwave Beam - Get both upgrades, no exceptions

  • 🎯 Precision Bolt - Both upgrades absolutely essential

  • Full suit upgrades - Don't even think about skipping these

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Rune Setup That Actually Works:

Rune Type Recommendation Why It Matters
Base Runes Saving Throw, Air Control, Chrono Strike Mobility is everything here
Support Rune Take Back Your safety net when things go wrong

Honestly, the Microwave Beam upgrades are non-negotiable. Without them, you'll be stuck in place for what feels like an eternity, and in this fight? Standing still equals death. The Precision Bolt? Oh man, those pesky eyeballs from the turrets become absolute nightmares without it.

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Phase One: The Dance Begins 💃

Okay, first phase - this is where we learn the rhythm. The Mutated Seraphim starts by throwing orbs at you, and here's the thing: shoot from range and dodge those orbs like your life depends on it (because it does).

Pro Tips for Phase One:

  • ❌ Avoid using Plasma Rifle or Ballista (save that energy ammo!)

  • ️ Use the platforms as shields - he raises two but only shoots from one

  • 👊 Never, EVER try to melee him (trust me on this one)

About halfway through, he'll start summoning demons. My advice? Ignore them unless you absolutely need resources. Chainsaw for ammo, flame belch for armor - otherwise, keep your eyes on the prize.

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Phase Two: Spirit Hunting 👻

This is where things get tricky. The boss is invincible here, so don't waste your ammo on him. He summons two Spirits - one in a Mancubus, another in a Prowler.

My Battle Plan:

  1. Immediately take cover behind the platform

  2. Deal with the Prowler first (Rocket Launcher or Full Auto Shotgun works wonders)

  3. Use Microwave Beam on the Spirit

  4. Handle the Mancubus using the platform as cover

Here's the kicker - after both Spirits are down, he'll glow orange and blue. You MUST glory kill him, or you'll be doing this entire phase all over again. Yeah, I learned that one the hard way...

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Phase Three: Platforming Hell 🏃‍♂️

Oh boy, this phase. The ground becomes electrified and poisoned, platforms catch fire, laser grids activate, and Cacodemons start flying around. It's pure chaos, but there's a rhythm to it.

Survival Pattern:

  • Leave platforms when they're on fire

  • Dodge grids while jumping

  • Kill one Cacodemon per platform

  • Rinse and repeat

The ground and flaming platforms won't kill you instantly, but taking damage here makes the next phases way harder. Focus on staying alive rather than dealing damage.

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Phase Four: Resource Management 🔄

Now we're getting to the good stuff. Three types of demons join the party: Zombies, Eyeballs, and Makyr Drones. Surprisingly, two of these actually help you more than hurt you.

Resource Strategy:

  • 🔋 Chainsaw Zombies for ammo (they spawn in pairs)

  • 💥 Headshot Makyr Drones with Precision Bolt for ammo explosions

  • 👁️ Two Precision Bolt shots take out Eyeballs

Resist the urge to go through the portals and attack from above. The Mutated Seraphim will teleport up there and wreck you. Stick to the bottom, whittle him down when he's visible, but mostly focus on managing the adds.

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Phase Five: The Final Countdown ⏳

We're almost there! The boss is immune again, and we've got two Spirits to deal with - one in a Prowler, one in a Pain Elemental.

Final Phase Checklist:

  • ✅ Use line of sight against Pain Elemental

  • ✅ Lure Prowler away from the action

  • ✅ Kill Prowler and Spirit first

  • ✅ Deal with Pain Elemental second

  • ✅ Use mobs for resources between Spirit kills

CRITICAL REMINDER: Don't kill an enemy with a Spirit until you're ready to immediately destroy that Spirit. If you mess this up, another demon of the same type spawns, and you're back to square one. Make sure you're full on energy ammo and won't be interrupted during Microwave Beam casts.

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Wrapping It Up 🎁

Look, I'm not gonna sugarcoat it - this fight is brutal. But with the right preparation and strategy, it's absolutely doable. The key is patience and resource management. Don't get greedy, don't take unnecessary risks, and most importantly - learn from each attempt.

Remember what worked for me:

  • Proper upgrades make all the difference

  • Each phase has a specific rhythm - learn it

  • Resource management is more important than dealing damage

  • Those Spirits? Handle them with care

You've got this, Slayer. Now go show that Mutated Seraphim who's boss! 💪

Recent trends are highlighted by Eurogamer, a leading source for European gaming news and expert reviews. Eurogamer's coverage of Doom Eternal's toughest boss battles, including the Mutated Seraphim, emphasizes the importance of mastering resource management and adapting to multi-phase encounters, echoing the strategies outlined in this guide for Ultra-Nightmare success.